LONDON - World number one and five-time champion Serena Williams has crashed to her earliest defeat at Wimbledon for nine years while Rafael Nadal, Roger Federer and Maria Sharapova sailed smoothly through.
Williams, the top seed, lost her third-round tie to French 25th seed Alize Cornet 1-6 6-3 6-4 in a Court One clash which had been held up for over four hours because of torrential rain which saw 45 matches wiped off the schedule.
Serena could have no complaints about an embarrassing defeat, which continued a disappointing campaign for the 17-time Grand Slam champion.
It was her earliest exit from the All England Club since 2005 when she lost to fellow American Jill Craybas at the same stage.
"Well, I think everyone in general plays the match of their lives against me. So I'm pretty sure that the next match, it won't be the same," Williams said.
"So I just have to be a hundred times better. If I'm not, then I'm in trouble."
Cornet, 24, goes on to face Canadian 13th seed Eugenie Bouchard on Monday in what will be her first appearance in the second week of Wimbledon.
Cornet, who had defeated Williams in Dubai earlier this year, celebrated by kissing the turf in jubilation.
"A few years ago I couldn't even play on grass. I was so bad," said the slender Frenchwoman.
"To beat Serena at Wimbledon, wow, it is just a dream. It is the biggest upset in the tournament because she is the world number one and has won here so many times."
In stark comparison, Nadal, Federer and Sharapova all secured fourth round spots playing under the Centre Court roof.
Nadal, the 2008 and 2010 champion, dropped the opening set for the third time in three matches before turning things around in a 6-7 (4/7), 6-1, 6-1, 6-1 victory over Kazakhstan's Mikhail Kukushkin, who had never won a Wimbledon match before this year.
Nadal, the 28-year-old winner of 14 Grand Slam titles, won 17 of the last 19 games against the world number 63 and goes on to face Australia's rising star Nick Kyrgios who beat Jir Vesely of the Czech Republic, 3-6 6-3 7-5 6-2.
Seven-time champion Federer breezed past Santiago Giraldo of Colombia, 6-3 6-1 6-3 and next faces either big-serving Polish 15th seed Jerzy Janowicz, a semi-finalist last year, or Tommy Robredo of Spain, seeded 23rd, for a place in the quarter-finals.
Sharapova, the 2004 champion, remained on course for a rare French Open and Wimbledon double after moving into the fourth round with a 6-3 6-0 victory over American Alison Riske.
The world number five next faces German ninth seed Angelique Kerber who beat Kirsten Flipkens of Belgium, 3-6 6-3 6-2.
Third seed Simona Halep of Romania reached the last 16 for the first time with a 6-4 6-1 win over Swiss teenager Belinda Bencic.